From October to November, IE dropped 1%, a drop bigger than the last four months. Firefox fell 0.07%. Safari went up 0.22% and Opera dipped 0.08%. Finishing first, Chrome gained 0.78%. It may sound like it's so little to matter, but if you look at the steady rise Chrome has been taking, I imagine it'll take over unless it slips or Google stops investing their resources in it.
Both seem unlikely, so therefore, prepare for a new king in my opinion.
If you don't already use chrome, give it a shot! I previously used Firefox, but the speed of Chrome is soooo much faster, it really is. If you use IE, it's night and day.
Try it out!